The Gunners manager has backed the young Englishmen to bounce back after enduring a torrid evening against Liverpool on Monday.
The former Southampton defender was up against the Belgian international Benteke, who gave Chambers a difficult time in the first half.
But Wenger has praised the ‘mentall strength’ he showed against the Brenden Rodgers physical side and said he will find his feet as the season progresses.
“He showed character. The positive of the night – he did not have the best performance in the first half – was the way he recovered,” he told reporters.
“He has lost a bit of confidence, compared to the player he was last year. Maybe it’s through not playing too much, the Under-21 tournament [with England this summer] did not help him too much, as he did not play at all.
“I have spoken to him and he’s a strong footballer, a dedicated player who is ready to work day and night. He has the talent to be a good player.”
Wenger admits that he contemplated substituting Chambers during the second half but maintains that senior players should have taken steps to protect the 20-year-old.
“I don’t think it would have killed him [to replace him],” said Wenger. “I did not sub him as I wanted to save my offensive options. It also gives him time to recover. But we wanted to win the game. He recovered quite well in the second half.