Southampton will look to bring an end to a recent run of bad results at home to an improving Manchester United side tonight.
Southampton lost both games during the last week, although were unfortunate to go down at the Emirates.
Alexis Sanchez scored an 89th minute winner for Arsenal, with Southampton reduced to 10 men after Toby Alderweireld went off injured with the visitors using all three subs.
Last weekend they were convincingly beaten at home by Manchester City, with Yaya Toure among the goalscorers.
Manchester United made it four wins in a row, with back to back home victories in the last seven days.
Robin van Persie was back on the scoresheet as they easily beat Hull City last weekend, although Angel Di Maria was replaced early on through injury.
It wasn’t as easy for United at home to Stoke during the midweek, with Juan Mata’s free-kick the difference in a 2-1 victory.
Both games last season finished 1-1, with Mata scoring United’s leveller in the clash at the St. Mary’s.
At Old Trafford, Dejan Lovren, now of Liverpool, scored a late header to earn Southampton an impressive point.
Alderweireld is a doubt after going off against Arsenal, with Morgan Schneiderlin also set to miss the clash.
Maya Yoshida will replace Alderweireld in the defence, whilst Jack Cork could be rushed back for the game.
Shane Long started ahead of Saido Mane and the former West Brom man looks set to keep his spot.
Wayne Rooney missed United’s win over Stoke, however Louis van Gaal has confirmed he will be fit for Monday’s clash.
Luke Shaw could be fit to face his former employers and would replace Ashley Young, who has done well as a temporary left-back.
Di Maria will miss the match, although Radamel Falcao has made two cameo appearances during the week.
Southampton: Forster; Clyne, Fonte, Yoshida, Bertrand; Cork, Davis, Wanyama; Tadic, Pelle, Long
Manchester United: De Gea; Valencia, Smalling, Rojo, Shaw; Carrick, Fellaini, Herrera; Mata, Rooney, Van Persie