Hull City need to win this game to have some hopes of avoiding a likely relegation to the Championship.
The Tigers have to win this game and then hope for other results going their way to stay in the Premier League for another season.
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Steve Bruce will be hoping for some favours from the club he captained once.
Louis van Gaal however, will be in no mood to do his counterpart any favours when the two teams meet this Sunday.
Hull City have not enjoyed a good season under their belt and a victory against Manchester United, who have improved significantly over the course of the season, seems highly unlikely.
The hosts need to win this game with Newcastle either losing or drawing their last game of the season, in order to avoid the drop.
Manchester United blew up the chance to finish above Arsenal in the table and avoid a Champions League draw by drawing against the Gunners last week.
Now the result of this game will bring no change to the standings of the club in the league.
Van Gaal can take this game as a chance to give his fringe players a chance to show that they deserve to stay with the club beyond the summer.
ith Memphis Depay already arriving at Old Trafford, and a few other high profiles arrival expected to join soon, futures of some Manchester United players are under threat.
The likes of Di Maria, Adnan Januzaj and Evans can start the game against Hull City to show that they got what it takes to be a Manchester United player.
Hull City are expected to field an unchanged side once more, while Jake Livermore remains suspended following positive drugs test.
Manchester United will not risk David de Gea with Victor Valdes expected to start in the goal for the visitors.