Latest England v Ireland odds from the Six Nations, plus team news and betting on the battle at Twickenham this afternoon (KO 16:00).
The third round of matches gets underway this weekend with the Triple Crown up for grabs.
Ireland and England will meet on Saturday at Twickenham with the Irish hoping to mark their first trip on the road under Joe Schmidt with their triple crown since 2009.
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England 1/2, Draw 20/1, Ireland 6/4
Italy 4/7, Draw 22/1, Scotland 13/8
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The Irish have already impressed in wins over Scotland and Wales and Schmidt will be keen to build on the strong performances to date.
Up against them is an England team that recovered from their disappointing last gasp defeat to the French in the opening round to beat Scotland in the Calcutta cup last time out.
Head Coach Stuart Lancaster has stuck with 14 of the men that won in Murrayfield with Bath tighthead David Wilson the only change.
Wilson comes in for the injured Dan Cole and his battle with Cian Healy is just one of a number of intriguing head to heads in what will be a very physical battle.
Ireland meanwhile have kept faith with Healy and the rest of the team that beat Wales last time out meaning Brian O’Driscoll will set the record for most appearances in test rugby as he turns out in green for the 139th time.
The evergreen centre will line up alongside his long-term rugby partner Gordon D’arcy with brother, Dave and Rob, Andrew Trimble, Conor Murray and Jonathan Sexton, so impressive last time out, competing the backline.
Up front the form of Peter O’Mahony will be key to any hopes Ireland has of a triple crown. The Munster man has been one of the star performers of the six nations so far and his physicality will be crucial to the Irish cause.
On the bench it is the name of Jordi Murphy that has garnered the most headlines. The Leinster man
The game is the standout game of the weekend and with so much at stake the home crowd are expected to play a large part in the game.
With that in mind, England hope to tap into the buzz surrounding the clash by parking the bus 25 yards further away from the gate, making their players walk through the Twickenham crowds to the dressing room.
Earlier in the day, Scotland will travel to Rome to face a plucky Italian side that has given Wales and France a stern test in their opening two games.
Both sides have yet to win and this matchup and the loser of this match will more than probably end up with a wooden spoon ensuring a tense and fraught affair at the Stadio Olimpico.
The Scottish became the first home side to fail to score in a 6 Nations in their abject defeat to England last time out and Scott Johnson and his men will be hoping for an improved performance as they look to build confidence in the team not to mention deter from the negative headlines that followed the Calcutta cup outing.
Both sides have made three changes from their last outing with Angelo Esposito Alessandro Zanni and Robert Barbieri all coming in for the Italians and Scott Lawson, Richie Gray and Johnnie Beattie all recalled by the Scottish.