England international Defoe played and scored in Spurs’ opening day defeat to Newcastle United on Saturday in what was Villas-Boas’ first competitive game in charge since taking over from Harry Redknapp.
The 29-year-old is the only senior striker available to the Portuguese tactician at present but is reportedly seeking a move away from the North London club after finding his opportunities limited last season.
And despite starting the new campaign in the first eleven that could change should Spurs sign a new forward with Emmanuel Adebayor and Leandro Damiao still on their radar.
Sunderland boss Martin O’Neill is said to be interested in bringing Defoe to the Stadium of Light whilst Aston Villa are also in the market for a new frontman to partner Darren Bent.
“He always has this killer instinct. He scored in midweek for his country, scored for us during pre-season and again here,” said Villas-Boas.
“He is showing that touch that we need up front. Jermain accepts that we are looking for one more striker because the team is in need of that, but when we have them all together the quality of the player is tremendous.
“It is a different situation for him now. I have nothing to do with anything that happened in the past. He is our striker, is playing extremely well, is full of confidence and has been deadly in front of goal.”
With any potential incomings hinging on the departure of Luka Modric to Real Madrid the final two weeks of the transfer window could prove to be frantic as Villas-Boas endeavours to tie up a new striker before the deadline passes.